產(chǎn)品屬性：
產(chǎn)品名稱 | TCMDC-135051 |
規(guī)格 | 5mg、10mM/1ml、50mg、100mg、200mg、500mg |
貨號 | EY-01Y9638 |
Cas No.: 2413716-15-9
別名: N/A
化學名: N/A
分子式: C29H33N3O3
分子量: 471.59
溶解度: DMSO: 250 mg/mL (530.12 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
TCMDC-135051 is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC50=320 nM)[1].[1]. Alam MM, et al. Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science. 2019 Aug 30;365(6456). pii: eaau1682.
特別提醒公司產(chǎn)品僅供科研使用
