產(chǎn)品屬性：
產(chǎn)品名稱 | SQ609 |
規(guī)格 | 25 mg、50 mg |
貨號(hào) | EY-01Y10304 |
Cas No.: 627052-25-9
別名: N/A
化學(xué)名: N/A
分子式: C22H38N2O
分子量: 346.55
溶解度: DMSO : 6.67 mg/mL (19.25 mM; ultrasonic and warming and heat to 60°C)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
SQ609 is a lead compound from a library of dipiperidines. SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells. SQ609 displays a potent antitubercular activity [1].In Mtb-infected macrophages in vitro, SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells[1].SQ609 (10 mg/kg; intravenous injection) completely prevents weight loss in the Mtb-infected animals and prolongs the therapeutic effect following drug withdrawal for another 10-15 days[1].[1]. Bogatcheva E, et al. Identification of SQ609 as a lead compound from a library of dipiperidines. Bioorg Med Chem Lett. 2011;21(18):5353-5357.
特別提醒公司產(chǎn)品僅供科研使用
