產(chǎn)品屬性：
產(chǎn)品名稱 | Sulfo-ara-F-NMN |
規(guī)格 | 5 mg、10 mg、50 mg、100 mg |
貨號 | EY-01Y10361 |
Cas No.: 1374663-29-2
別名: N/A
化學名: N/A
分子式: C11H14FN2O6PS
分子量: 352.28
溶解度: DMSO: 210 mg/mL (596.12 mM)
儲存條件: -20°C, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production[1].Sterile alpha and Toll/interleukin-1 receptor motif-containing 1 (SARM1) is an adaptor protein in the Toll-like receptor pathway. Sulfo-ara-F-NMN activates SARM1 to produce cyclic ADP-ribose and induces non-apoptotic cell death[1].[1]. Zhao ZY, et al. A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death. iScience. 2019 May 31;15:452-466.
特別提醒公司產(chǎn)品僅供科研使用
