產品屬性：
產品名稱 | YKL-06-061 |
規格 | 10mM*1mL in DMSO、5mg、10mg、50mg、100mg、200mg、500mg |
貨號 | EY-01Y10508 |
Cas No.: 2172617-15-9
別名: N/A
化學名: N/A
分子式: C30H37N7O2
分子量: 527.66
溶解度: DMSO: 62.5 mg/mL (118.45 mM); H2O: < 0.1 mg/mL (insoluble)
儲存條件: Store at -20°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1].IC50: 6.56 nM/1.77 nM/20.5 nM (SIK1/2/3)[1].[1]. Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184.
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