產品屬性：
產品名稱 | RS 09 (trifluoroacetate salt) |
規(guī)格 | 500 μg、1 mg、5 mg、10 mg |
貨號 | EY-01Y10677 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C31H49N9O9·XCF3COOH
分子量: 691.8
溶解度: DMF: 1 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
RS 09 is a peptide agonist of toll-like receptor 4 (TLR4).1 It activates NF-κB in a concentration-dependent manner in a secreted alkaline phosphatase (SEAP) assay using TLR4-expressing HEK293 cells and induces NF-κB nuclear translocation in the same cells. It also induces cytokine secretion from RAW 264.7 cells. RS 09 (25 μg/animal) acts as an adjuvant in mice vaccinated with a KLH-conjugated X-15 antigen, with no antibodies produced in mice receiving RS 09 without the antigen.1.Shanmugam, A., Rajoria, S., George, A.L., et al.Synthetic toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvantsPLoS One7(2)e30839(2012)
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