產品屬性：

Cas No.: 152286-31-2

別名: Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe

化學名: Amyloid β-Peptide (10-20) (human)

分子式: C71H99N17O16

分子量: 1446.67

溶解度: ≥ 144.7mg/mL in DMSO

儲存條件: Desiccate at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

產品描述：

The amyloid β-peptide (Aβ) has a central role in initiating neurodegeneration in Alzheimer disease (AD) 1. It is widely believed to be an incidental catabolic byproduct of the amyloid β protein precursor (APP) with no normal physiological function.2

Aβ has been shown to be a ligand for a number of different receptors and other molecules3-5.   It is transported between tissues and across the blood brain barrierby complex trafficking pathways6.   Aβ is modulated in response to a variety of environmental stressors and is able to induce pro-inflammatory activities7.

Soluble amyloid β-peptide fragment that is a substrate for gelatinase A/type IV collagenase/MMP-2 and APP secretase; cleaved between Lys16 and Leu17.

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