產品屬性：
產品名稱 | QWF |
規格 | 5 mg |
貨號 | EY-01Y13681 |
Cas No.: 126088-82-2
別名: N/A
化學名: N/A
分子式: C38H43N5O8
分子量: 697.78
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Tripeptide substance P (SP) antagonist (IC50 = 90 μM). Also inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Inhibits SP-induced IgE-independent degranulation of mast cells in vitro. Inhibits compound 48/80-induced MRGPRX2 activation and scratching in mice in vivo.Hagiwara et al (1992) Studies on neurokinin antagonists. 1. The design of novel tripeptides possessing the glutaminyl-D-tryptophylphenylalanine sequence as substance P antagonists. J.Med.Chem. 35 2015 PMID:1375965 |Azimi et al (2016) Dual action of neurokinin-1 antagonists on Mas-related GPCRs. JCI Insight. 1 e89362 PMID:27734033
特別提醒公司產品僅供科研使用
