產(chǎn)品屬性：
產(chǎn)品名稱 | SIRT-IN-3 |
規(guī)格 | 10mM*1 mL in DMSO、10mg |
貨號(hào) | EY-01Y14785 |
Cas No.: 1211-19-4
別名: N/A
化學(xué)名: N/A
分子式: C13H12N2O
分子量: 212.25
溶解度: DMSO: 250 mg/mL (1177.86 mM)
儲(chǔ)存條件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
SIRT-IN-3 is a potent SIRT inhibitor, with an IC50 of 17 μM for SIRT1. SIRT-IN-3 shows about 4-fold and 14-fold selectivity for SIRT1 over SIRT2 and SIRT3, respectively (IC50 of 74 μM and 235 μM for SIRT2 and SIRT3, respectively)[1].SIRT-IN-3 (Compound 7) (30-300 μM; 8 hours) causes p53 acetylation in in HCT116 cells[1].[1]. Suzuki T, et al. 2-Anilinobenzamides as SIRT inhibitors. ChemMedChem. 2006 Oct;1(10):1059-62.
特別提醒公司產(chǎn)品僅供科研使用
