產(chǎn)品屬性：
產(chǎn)品名稱 | Raloxifene 4'-Glucuronide |
規(guī)格 | 1mg |
貨號 | EY-01Y15055 |
Cas No.: 182507-22-8
別名: N/A
化學名: N/A
分子式: C34H35NO10S
分子量: 649.7
溶解度: DMSO: slightly soluble,Methanol: slightly soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Raloxifene 4'-glucuronide is a metabolite of the selective estrogen receptor modulator raloxifene . It is formed from raloxifene via the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1, UGT1A8, and UGT1A10. It binds to the estrogen receptor with an IC50 value of 370 nM. Raloxifene 4'-glucuronide inhibits the voltage-gated potassium channel Kv4.3 by 6.2 and 20.1% when used at concentrations of 10 and 30 μM, respectively.
特別提醒公司產(chǎn)品僅供科研使用
