產品屬性：
產品名稱 | Thiocolchicine |
規格 | 5mg、10mg、25mg、100mg |
貨號 | EY-01Y15292 |
Cas No.: 2730-71-4
別名: N/A
化學名: N/A
分子式: C22H25NO5S
分子量: 415.5
溶解度: DMSO: soluble,Ethanol: soluble,Methanol: soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Thiocolchicine is an inhibitor of microtubule assembly (IC50 = 2.5 μM) and a derivative of colchicine . It inhibits binding of colchicine to tubulin (Ki = 0.7 μM in a radioligand binding assay). Thiocolchicine inhibits proliferation of MDA-MB-231 and multidrug resistant (MDR) MCF-7 ADRr breast cancer cells (IC50s = 0.6 and 400 nM, respectively) as well MDR CEM-VBL leukemia cells (IC50 = 50 nM).
特別提醒公司產品僅供科研使用
