產(chǎn)品屬性：
產(chǎn)品名稱 | Triclabendazole-13C-d3 |
規(guī)格 | 500 μg、1 mg、5 mg |
貨號 | EY-01Y15426 |
Cas No.: N/A
別名: N/A
化學(xué)名: N/A
分子式: C13[13C]H6D3Cl3N2OS
分子量: 363.7
溶解度: Acetonitrile: soluble,DMSO: soluble,Methanol: soluble
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Triclabendazole-13C-d3 is intended for use as an internal standard for the quantification of triclabendazole by GC- or LC-MS. Triclabendazole is a benzimidazole anthelmintic.1 It eliminates both immature and adult flukes in a sheep model of F. hepatica infection when administered at a dose of 10 mg/kg.2 Triclabendazole (5 μM) also protects against glucose- or α-synuclein-induced apoptosis in S. cerevisiae via inhibition of adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A (PKA) nutrient sensing pathway.3 1.Shrifi, Y., Farahnak, A., Golestani, A., et al.Triclabendazole effect on protease enzyme activity in the excretory- secretory products of Fasciola hepatica in vitroIran. J. Parasitol.9(1)107-113(2014)
2.Smeal, M.G., and Hall, C.A.The activity of triclabendazole against immature and adult Fasciola hepatica infections in sheepAust. Vet. J.60(11)329-331(1983)
3.Lee, Y.J., Burlet, E., Wang, S., et al.Triclabendazole protects yeast and mammalian cells from oxidative stress: Identification of a potential neuroprotective compoundBiochem. Biophys. Res. Commun.414(1)205-208(2011)
特別提醒公司產(chǎn)品僅供科研使用
