產(chǎn)品屬性：
產(chǎn)品名稱 | Rheb inhibitor NR1 |
規(guī)格 | 5mg |
貨號 | EY-01Y15522 |
Cas No.: 2216763-38-9
別名: N/A
化學(xué)名: N/A
分子式: C25H19BrCl2N2O3S
分子量: 578.3
溶解度: DMSO: 100 mg/mL (172.92 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Rheb inhibitor NR1 is a Rheb inhibitor with an IC50 of 2.1 μM in the Rheb-IVK assay. Rheb inhibitor NR1 also is a selective mTORC1 inhibitor. NR1 inhibits the phosphorylation of T389pS6K1 and increases the phosphorylation of S473pAKT in a dose-dependent manner[1].[1]. Mahoney SJ, et al. A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nat Commun. 2018 Feb 7;9(1):548.
特別提醒公司產(chǎn)品僅供科研使用
