產品屬性：
產品名稱 | TASP 0390325 |
規(guī)格 | 10 mg、50 mg |
貨號 | EY-01Y16266 |
Cas No.: 1642187-96-9
別名: N/A
化學名: N/A
分子式: C25H29ClFN5O4.HCl
分子量: 554.44
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Potent and selective V1B receptor antagonist (IC50 = 2.22 nM for rat pituitary receptor). Exhibits no significant affinity for 85 other receptors, ion channels and transporters at 10 μM, including V1A and V2. Increases ACTH levels in rats. Orally bioavailable. Antidepressant and anxiolytic.Iijima et al (2014) Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin V1B receptor antagonists: TASP0233278 and TASP0390325. Br J Pharmacol. 171 3511 PMID:24654684
特別提醒公司產品僅供科研使用
