產品屬性：
產品名稱 | UDM-001651 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y16439 |
Cas No.: 1477497-01-0
別名: N/A
化學名: N/A
分子式: C28H23N3O5S
分子量: 513.56
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM). UDM-001651 shows antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP)[1].IC50: 4 nM (PAR4)[1]Kd: 1.4 nM (PAR4)[1][1]. Miller MM, et al. Discovery of Potent Protease-Activated Receptor 4 Antagonists with in vivo Antithrombotic Efficacy. J Med Chem. 2019 Jun 27.
特別提醒公司產品僅供科研使用
