產(chǎn)品屬性：
產(chǎn)品名稱 | Phenylacetyl-Coenzyme A (sodium salt) |
規(guī)格 | 1 mg、5 mg |
貨號(hào) | EY-01Y17115 |
Cas No.: N/A
別名: N/A
化學(xué)名: N/A
分子式: C29H42N7O17P3S·XNa
分子量: 885.7
溶解度: PBS (pH 7.2): 10 mg/ml
儲(chǔ)存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Phenylacetyl-coenzyme A (CoA) is a key intermediate in aerobic catabolism of phenylacetate in bacteria such as Pseudomonas, when cultured in minimal media using phenylacetate as the sole carbon source.1 It is a precursor in the synthesis of the antibiotic penicillin G found in industrial strains of P. chrysogenum. Phenylacetyl-CoA also acts as an effector molecule of the TetR family transcriptional repressor PaaR in T. thermophilus and the GntR family transcriptional regulator PaaX in E. coli and Pseudomonas, binding to each protein to induce derepression of various genes.21.Mi?ambres, B., Martínex-Blanco, H., Olivera, E.R., et al.Molecular cloning and expression in different microbes of the DNA encoding Pseudomonas putida U phenylacetyl-CoA ligase. Use of this gene to improve the rate of benzylpenicillin biosynthesis in Penicillium chrysogenumJ. Biol. Chem.271(52)33531-33538(1996)
2.Sakamoto, K., Agari, Y., Kuramitsu, S., et al.Phenylacetyl coenzyme A is an effector molecule of the TetR family transcriptional repressor PaaR from Thermus thermophilus HB8J. Bacteriol.193(17)4388-4395(2011)
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