產(chǎn)品屬性：
產(chǎn)品名稱 | Tasimelteon-d5 |
規(guī)格 | 1mg、5mg |
貨號 | EY-01Y17825 |
Cas No.: 1962124-51-1
別名: N/A
化學(xué)名: N/A
分子式: C15H14D5NO2
分子量: 250.4
溶解度: Acetonitrile: soluble,DMF: soluble,DMSO: soluble,Methanol: soluble
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Tasimelteon-d5 is intended for use as an internal standard for the quantification of tasimelteon by GC- or LC-MS. Tasimelteon is a melatonin (MT) receptor agonist.1 It selectively binds MT1 and MT2 receptors (Kis = 0.304 and 0.069 nM, respectively, in NIH3T3 cells expressing the recombinant human receptors) over a panel of 160 additional receptors and enzymes at 10 μM. Tasimelteon inhibits forskolin-induced cAMP accumulation with EC50 values of 0.79 and 1 nM in NIH3T3 cells expressing the MT1 or MT2 receptor, respectively. Formulations containing tasimelteon have been used in the treatment of non-24-hour sleep-wake disorder.1.Lavedan, C., Forsberg, M., and Gentile, A.J.Tasimelteon: A selective and unique receptor binding profileNeuropharmacology91142-147(2015)
特別提醒公司產(chǎn)品僅供科研使用
