產品屬性：
產品名稱 | Heliquinomycin |
規(guī)格 | 1mg |
貨號 | EY-01Y19891 |
Cas No.: 178182-49-5
別名: N/A
化學名: N/A
分子式: C33H30O17
分子量: 698.6
溶解度:
儲存條件: 4°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Heliquinomycin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities.1 It is active against a variety of Gram-positive bacteria, including strains of B. anthracis, B. subtilis, and methicillin-sensitive or -resistant S. aureus (MICs = <0.05-0.39 μg/ml). Heliquinomycin inhibits the activity of DNA helicase with a Ki value of 6.8 μM. It reduces the growth of L1210 leukemia, B16 melanoma, and FS-3 fibrosarcoma cells (IC50s = 0.97, 0.89, and 0.83 μg/ml, respectively). 1.Chino, M., Nishikawa, K., Umekita, M., et al.Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2 I. Taxonomy, production, isolation, physico-chemical properties and biological activitiesJ. Antibiot. (Tokyo)49(8)752-757(1996)
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