產(chǎn)品屬性：
產(chǎn)品名稱 | Fuscin |
規(guī)格 | 1mg、5mg、10mg |
貨號 | EY-01Y20680 |
Cas No.: 83-85-2
別名: N/A
化學(xué)名: N/A
分子式: C15H16O5
分子量: 276.3
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities. It inhibits binding of the ADP/ATP translocase inhibitor atractyloside to rat liver mitochondria in an ADP-dependent manner when used at a concentration of 50 μM in a radioligand binding assay. Fuscin (20 μM) reduces the glutathione content of rat liver mitochondria to 28% of controls and inhibits NADH oxidation in sonicated pigeon heart mitochondria preparations in a concentration-dependent manner. It competes with macrophage inflammatory protein 1α (MIP-1α) for binding to CCR5 chemokine receptors in vitro with an IC50 value of 21 μM.
特別提醒公司產(chǎn)品僅供科研使用
