產品屬性：
產品名稱 | H-L-Photo-lysine hydrochloride |
規格 | 5mg、10mg、50mg |
貨號 | EY-01Y20792 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C11H21ClN4O4
分子量: 308.76
溶解度: N/A
儲存條件: N/A
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
H-L-Photo-lysine hydrochloride is a diazirine-containing lysine amino acid and is a photo-cross-linker. H-L-Photo-lysine hydrochloride can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. H-L-Photo-lysine hydrochloride acts as a UV light-activated photo-crosslinking probe[1][2][3].Photo-lysine, which is readily incorporated into proteins by native mammalian translation machinery, can be used to capture and identify proteins that recognize lysine post-translational modifications (PTMs), including 'readers' and 'erasers' of histone modifications[2].[1]. Ai HW, et al. Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid. Chembiochem. 2011 Aug 16;12(12):1854-7.
[2]. Chatterjee A, et al. Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11803-8.
[3]. Yang T, et al. Photo-lysine captures proteins that bind lysine post-translational modifications. Nat Chem Biol. 2016 Feb;12(2):70-2.
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